FR022491

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  • Summary
  • Sequence
  • Secondary Structure
Evidence Mapping [blat]
blat with identity=99, coverage=90 and no-repeat
Evidence Sequence Similarity [highly similar]
Almost same sequences with one mismatch or one gap
Summary
ID FR022491
Description C/D box guide small nucleolar RNA (snoRNA) HBII-52-40 / SNORD115-40
Accession AC100774 , AC124303 , AF250841 , NR_003355
Sequence Ontology C_D_box_snoRNA
Organism
Homo sapiens human , man
Genome Mapping
human(hg18)           1 region chr15:23039854-23039935(+) 
Cross Reference
Rfam v8.1 RF00105
snoRNA-LBME-db release3 HBII-52-40
RNAdb v2.0 SNO1328
Gene Association / Sense Overlap / Intron
human(hg18) AF400501 (uc001zae.2 )
Gene Association / Sense Overlap / 3'UTR
human(hg18) NR_003355 (uc001zai.1 )
Sequence Similarity
highly similar FR053213   C/D box guide small nucleolar RNA (snoRNA) HBII-52-13 / SNORD115-13
FR137651   C/D box guide small nucleolar RNA (snoRNA) HBII-52-9 / HBII-52-12 / SNORD115-9 / SNORD115-12
FR234599   C/D box guide small nucleolar RNA (snoRNA) HBII-52-21 / SNORD115-21

MicroArray / Affymetrix GeneChip Exon Array / hg18
ProbeTranscript ClusterProbe Locus
1599529 3584740  chr15:23039881-23039905(+) 
775248 3584740  chr15:23039884-23039908(+) 
3240053 3584740  chr15:23039903-23039927(+) 
5464803 3584740  chr15:23039911-23039935(+) 

Reference
The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C.
Kishore S. and Stamm S.
Science 311 (5758), 230-2 (2006)
snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs.
Lestrade L. and Weber MJ.
Nucleic Acids Res 34 (Database issue), D158-62 (2006)
ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs.
Vitali P.,Basyuk E.,Le Meur E.,Bertrand E.,Muscatelli F.,Cavaillé J. and Huttenhofer A.
J Cell Biol 169 (5), 745-53 (2005)
Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome.
Runte M.,Varon R.,Horn D.,Horsthemke B. and Buiting K.
Hum Genet 116 (3), 228-30 (2005)
RNAdb--a comprehensive mammalian noncoding RNA database.
Pang KC.,Stephen S.,Engström PG.,Tajul-Arifin K.,Chen W.,Wahlestedt C.,Lenhard B.,Hayashizaki Y. and Mattick JS.
Nucleic Acids Res 33 (Database issue), D125-30 (2005)
Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region.
Cavaillé J.,Seitz H.,Paulsen M.,Ferguson-Smith AC. and Bachellerie JP.
Hum Mol Genet 11 (13), 1527-38 (2002)
The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A.
Runte M.,Hüttenhofer A.,Gross S.,Kiefmann M.,Horsthemke B. and Buiting K.
Hum Mol Genet 10 (23), 2687-700 (2001)
Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization.
Cavaillé J.,Buiting K.,Kiefmann M.,Lalande M.,Brannan CI.,Horsthemke B.,Bachellerie JP.,Brosius J. and Hüttenhofer A.
Proc Natl Acad Sci U S A 97 (26), 14311-6 (2000)

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