fRNAdb - Detail Page [FR249972]

FR249972

Summary
Sequence
Secondary Structure

Evidence Mapping [blat]

blat with identity=99, coverage=90 and no-repeat

Evidence Sequence Similarity [highly similar]

Almost same sequences with one mismatch or one gap

Summary
ID	FR249972
Description	c-myc internal ribosome entry site (IRES)
Accession	K01909
Sequence Ontology	internal_ribosome_entry_site
Organism
Homo sapiens	human , man
Genome Mapping
human(hg18) 1 region	chr8:128817672-128817973(+)
Cross Reference
Rfam v8.1	RF00216
Gene Association / Sense Overlap / 5'UTR
human(hg18)	MYC (uc003ysh.1 , uc003ysi.1 )
Gene Association / Sense Overlap / Intron
human(hg18)	MYC (uc003ysh.1 )
Sequence Similarity
highly similar	FR044232 c-myc internal ribosome entry site (IRES)
highly similar	FR180713 c-myc internal ribosome entry site (IRES)

OMIM
ID	Title	Locus
190080	V-MYC AVIAN MYELOCYTOMATOSIS VIRAL ONCOGENE HOMOLOG; MYC ONCOGENE MYC AVIAN MYELOCYTOMATOSIS VIRAL ONCOGENE HOMOLOG PROTOONCOGENE HOMOLOGOUS TO MYELOCYTOMATOSIS VIRUS	8q24.12-q24.13(chr8:119200001-127300000)

MicroArray / Affymetrix GeneChip Exon Array / hg18
Probe	Transcript Cluster	Probe Locus
208420	3115504	chr8:128817834-128817858(+)
4627018	3115504	chr8:128817837-128817861(+)
2622200	3115504	chr8:128817839-128817863(+)
4214550	3115504	chr8:128817844-128817868(+)
6406096	3115504	chr8:128817896-128817920(+)
3541142	3115504	chr8:128817911-128817935(+)

Reference
Derivation of a structural model for the c-myc IRES. Le Quesne JP.,Stoneley M.,Fraser GA. and Willis AE. J Mol Biol 310 (1), 111-26 (2001)