• Summary
  • Sequence
  • Secondary Structure
Evidence Mapping [blat]
blat with identity=99, coverage=90 and no-repeat
ID FR293930
Description C/D box guide small nucleolar RNA (snoRNA) HBII-52-22 / SNORD115-22
Accession AC100774 , AC124303 , AF250841 , NR_003314
Sequence Ontology C_D_box_snoRNA
Homo sapiens human , man
Genome Mapping
human(hg18)           1 region chr15:23006158-23006239(+) 
Cross Reference
Rfam v8.1 RF00105
NONCODE v1.0 u1080
snoRNA-LBME-db release3 HBII-52-22
Gene Association / Sense Overlap / Intron
human(hg18) AF400498 (uc010ayo.1 ), NR_003313 (uc001yzq.1 ), AF400497 (uc001yzk.1 )
Gene Association / Sense Overlap / 3'UTR
human(hg18) NR_003314 (uc001yzr.1 )
Sequence Similarity

MicroArray / Affymetrix GeneChip Exon Array / hg18
ProbeTranscript ClusterProbe Locus
4717062 3584740  chr15:23006165-23006189(+) 
5777500 3584740  chr15:23006169-23006193(+) 
1870889 3584740  chr15:23006185-23006209(+) 
464777 3584740  chr15:23006209-23006233(+) 

The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C.
Kishore S. and Stamm S.
Science 311 (5758), 230-2 (2006)
snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs.
Lestrade L. and Weber MJ.
Nucleic Acids Res 34 (Database issue), D158-62 (2006)
ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs.
Vitali P.,Basyuk E.,Le Meur E.,Bertrand E.,Muscatelli F.,Cavaillé J. and Huttenhofer A.
J Cell Biol 169 (5), 745-53 (2005)
Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome.
Runte M.,Varon R.,Horn D.,Horsthemke B. and Buiting K.
Hum Genet 116 (3), 228-30 (2005)
NONCODE: an integrated knowledge database of non-coding RNAs.
Liu C.,Bai B.,Skogerbø G.,Cai L.,Deng W.,Zhang Y.,Bu D.,Zhao Y. and Chen R.
Nucleic Acids Res 33 (Database issue), D112-5 (2005)
Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region.
Cavaillé J.,Seitz H.,Paulsen M.,Ferguson-Smith AC. and Bachellerie JP.
Hum Mol Genet 11 (13), 1527-38 (2002)
The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A.
Runte M.,Hüttenhofer A.,Gross S.,Kiefmann M.,Horsthemke B. and Buiting K.
Hum Mol Genet 10 (23), 2687-700 (2001)
Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization.
Cavaillé J.,Buiting K.,Kiefmann M.,Lalande M.,Brannan CI.,Horsthemke B.,Bachellerie JP.,Brosius J. and Hüttenhofer A.
Proc Natl Acad Sci U S A 97 (26), 14311-6 (2000)
Archaeal homologs of eukaryotic methylation guide small nucleolar RNAs: lessons from the Pyrococcus genomes.
Gaspin C.,Cavaillé J.,Erauso G. and Bachellerie JP.
J Mol Biol 297 (4), 895-906 (2000)
The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions.
Balakin AG.,Smith L. and Fournier MJ.
Cell 86 (5), 823-34 (1996)