fRNAdb::RNAz Track Settings

fRNAdb::RNAz track

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Data last updated: 2011-12-22

Description

This track shows conserved non-coding regions predicted by RNAz [1,2].

This track is prepared to give interoperability with the functional RNA database [3] v3.0.

Methods

Short sequences (shorter than 30nt) are aligned to genome by SeqMap [4] with 0 mismatch, no-gap and no-repeat.

Other sequences are aligned to genome by BLAT [5] with identity>=99, coverage>=90 and no-repeat.

And limit results to predicted positions by RNAz.

References

  [1] Washietl S, Hofacker IL, Lukasser M, Huttenhofer A, Stadler PF.
      Mapping of conserved RNA secondary structures predicts thousands of functional noncoding RNAs in the human genome.
      Nat Biotechnol. 2005 Nov;23(11):1383-90.
  [2] Washietl S, Hofacker IL, Stadler PF.
      Fast and reliable prediction of noncoding RNAs.
      Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2454-9. Epub 2005 Jan 21.
  [3] Kin T, Yamada K, Terai G, Okida H, Yoshinari Y, Ono Y, Kojima A, Kimura Y, Komori T, Asai K.
      fRNAdb: a platform for mining/annotating functional RNA candidates from non-coding RNA sequences.
      Nucleic Acids Res. 2007 Jan;35(Database issue):D145-8.
  [4] Jiang H, Wong WH
      SeqMap: mapping massive amount of oligonucleotides to the genome.
      Bioinformatics. 2008 Oct 15;24(20):2395-6. Epub 2008 Aug 12.
  [5] Kent WJ.
      BLAT--the BLAST-like alignment tool.
      Genome Res. 2002 Apr;12(4):656-64.