fRNAdb::EvoFold Track Settings

fRNAdb::EvoFold track

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Data last updated: 2011-12-19

Description

This track shows conserved non-coding regions predicted by EvoFold [1].

This track is prepared to give interoperability with the functional RNA database [2] v3.0.

Methods

Short sequences (shorter than 30nt) are aligned to genome by SeqMap [3] with 0 mismatch, no-gap and no-repeat.

Other sequences are aligned to genome by BLAT [4] with identity>=99, coverage>=90 and no-repeat.

And limit results to positions of EvoFold track in UCSC Genome Browser.

References

  [1] Pedersen JS, Bejerano G, Siepel A, Rosenbloom K, Lindblad-Toh K, Lander ES, Kent J, Miller W, Haussler D.
      Identification and classification of conserved RNA secondary structures in the human genome.
      PLoS Comput Biol. 2006 Apr;2(4):e33.
  [2] Kin T, Yamada K, Terai G, Okida H, Yoshinari Y, Ono Y, Kojima A, Kimura Y, Komori T, Asai K.
      fRNAdb: a platform for mining/annotating functional RNA candidates from non-coding RNA sequences.
      Nucleic Acids Res. 2007 Jan;35(Database issue):D145-8.
  [3] Jiang H, Wong WH
      SeqMap: mapping massive amount of oligonucleotides to the genome.
      Bioinformatics. 2008 Oct 15;24(20):2395-6. Epub 2008 Aug 12.
  [4] Kent WJ.
      BLAT--the BLAST-like alignment tool.
      Genome Res. 2002 Apr;12(4):656-64.